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However, this does not mean the combination is without potential concerns or that it has been thoroughly studied in clinical trials

The health effects of long-term use of these medications for weight loss are unknown and still in clinical trials

doi: 10.1016/j.ijcard.2007.12.064, PMID: [DOI] [PubMed] [Google Scholar] Nkadimeng S
And they also work in the appetite center of the brain to help curb food cravings and food noise (constant nagging thoughts of food and eating)

Zhou, H

(2005) The cytoplasmic domain close to the transmembrane region of the glucagon-like peptide-1 receptor contains sequence elements that regulate agonist-dependent internalisation
