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Some may start with even lower doses if compounded formulations are available

Liraglutide injection The Safety and Clinical Adiposity Liraglutide Evidence (SCALE) trial was a randomized, double-blind, multicenter, international clinical trial that included 3,731 participants who were randomly assigned 2:1 to 3 mg liraglutide or placebo, both including lifestyle modifications

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The next phase of research is already underway: brain-penetrant GLP-1s, intranasal delivery, head-to-head neurocognitive trials, and combination approaches that pair metabolic repair with targeted neurobiology

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