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In the phase II trial published in the New England Journal of Medicine (2023), retatrutide demonstrated substantial weight loss efficacy, with participants achieving up to approximately 24% mean body weight reduction at the highest doses over 48 weeks

Psychological risks include disordered eating patterns

It is more common in children and young adults, while type 2 is more prevalent in people over 40

The regulatory effect of TH on glucose homeostasis was also evaluated by using intraperitoneal glucose tolerance test (GTT)