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Randomisation and Study Treatment Participants were randomised in a 1:1 ratio to either active treatment with exenatide (Byetta) or placebo using a computer-generated randomisation list compiled by the Birmingham Clinical Trials Unit

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Do not take a double dose to make up for a missed dose

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All the participants underwent a series of tests to measure their weight, blood glucose, plasma insulin and glucagon levels

The angiogenic effect is not direct on isolated cells in culture but appears in vivo when blood vessels and surrounding tissue are present (Brcic et al., 2009)