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Although GI AEs occurred more frequently with semaglutide 2.4 mg than with placebo across STEP 14, the vast majority of GI AEs reported were nonserious and mildtomoderate in severity, and did not necessitate dose reduction or discontinuation

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Then TRIUMPH-1 in May 2026: 28.3% in 2,339 general obesity patients at 80 weeks, confirming the results are consistent and reproducible across a much larger, more representative population

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This microorganism is known for its ability to break down mucin (a component of the gut lining), contributing to gut barrier health and metabolic balance
