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911 Although these findings provide insight into the potential relationship between GLP-1RAs and cancer risk, all existing studies have focused on comparisons among glucose-lowering drugs (GLDs) in patients with T2D, leaving uncertainty regarding their potential role in cancer prevention in individuals with obesity regardless of diabetes status

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( ad ) Representative dose-response curves of cAMP assays in cells expressing human GIPR (A), human GLP-1R (B), mouse GIPR (C), or mouse GLP-1R (D)