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Unlike the current widely used medications such as Ozempic and Mounjaro that target the GLP-1 pathway alone, retatrutide, known as a GLP-3, targets three pathways related to metabolism: GIP, GLP-1, and glucagon

This should be considered when treating patients, with impaired renal function as nausea, vomiting, and diarrhoea may cause dehydration which could cause a deterioration of renal function

The original GLP1.

SF researchers are now investigating whether the weight loss drugs can effectively help treat amphetamine addiction.

After two months, there was decrease in weight by 12 kg, body fat percent by 15%, visceral fat by 7%, and a reduction in insulin dose, glycemic variability, and HbA1c

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