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Additionally, in a post-hoc analysis of the SURPASS-4 trials, tirzepatide showed a slower rate of eGFR decline and lower urinary albumin creatinine values as compared to patients who were treated with glargine insulin [75, 76]

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Overall, strong preclinical data and early biomarker signals provide an encouraging rationale for GLP-1RAs in PD

Sept 21: In a setback for Intarcia Therapeutics, the FDAs Endocrinologic and Metabolic Drugs Advisory Committee voted unanimously that the benefits of its drug-device combination for Type 2 diabetes, ITCA 650, did not outweigh the risks

Difficulty Sitting Still: The urge to move the legs can make it challenging to sit still for extended periods, which may be problematic in jobs that require prolonged periods of desk work or meetings