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How tirzepatide addresses cardiovascular risk The Jorge 2026 study demonstrated that GLP-1 receptor agonists were associated with significantly lower risks of major adverse cardiovascular events in lupus patients compared to DPP-4 inhibitors

Both medications are stimulants that work by raising levels of dopamine and norepinephrine in the brain

Subjects without events of interest were censored at the end of their in-trial period

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The GLP-1 response from dietary EVOO, while statistically significant, is part of the normal postprandial hormonal cascade -- a nudge, not a pharmacological override