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As part of the incretin hormones, GLP-1 has three known mechanisms of action: activating glucose-dependent insulin secretions, thereby reducing plasma glucose, suppressing glucagon secretion, and delaying gastric emptying [3]

This information can support a more personalized conversation with a provider about whether continued treatment, alternate strategies, or intensive lifestyle support would be most appropriate for long-term success

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You can have effective weight loss alongside mild constipation

Eligibility requirements include: a type 2 diabetes diagnosis, commercial or private insurance that covers Rybelsus, age 18 or older, and US residency

In summary, insulin icodec offers similar or better glycaemic efficacy compared with daily basal insulin in type 2 diabetes, with good tolerability and encouraging safety results related to hypoglycaemia
