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In clinical trials, about 11% of people taking Wegovy reported feeling fatigued or weak, more than double reported by the placebo group

The Sphincter of Oddi is controlled by cholecystokinin (CCK) release in response to a meal, and it is also affected by other gastrointestinal peptides such as gastrin, secretin, motilin, and octreotide

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Others find themselves spiraling into emotional eating

In some cases, external hemorrhoids may thrombose (form a blood clot), causing severe pain and a firm lump near the anus

Patients with T2D were shown to have an impaired incretin effect [36], and this is an important contributor to the pathologies associated with T2D
