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Muscle fiber cross-sectional area (CSA) was quantified from H&E stained sections of TA muscles, revealing that muscle fibers of bimagrumab-treated animals were significantly larger than those of control animals, and average CSA of both control and bimagrumab-treated animals were larger than those of animals treated with semaglutide (Figure 3F,G)

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"A clinician may consider prescribing this medicine 'off-label' if they think it would benefit a patient with PCOS, but this would need a careful discussion with them about the benefits and potential risks," Balen said

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