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* * Clinical Trial Data Reference: Wegovy Pill (oral semaglutide) weight loss of 14%-16.6% reflects OASIS trials: OASIS 1(50mg, 68 wks) yielded a 15.1% mean reduction
SA node effect shud be right from beginning, why sympathetic effect on SA shows after a lag at 24 weeks, also if it's as shown in graph peaks after hiatus is this due to drug induced Increased basal metabolic rate(obvioous will be increased HR)

A randomized trial investigating the pharmacokinetics, pharmacodynamics, and safety of subcutaneous semaglutide once-weekly in healthy male Japanese and caucasian subjects

doi: 10.1089/chi.2025.0007
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