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The study duration spanned 68 weeks, with most significant loss occurring during the first 16 weeks as the dose was gradually increased from starting levels

Most patients experience natural slowdowns in weight loss velocity around weeks 812, weeks 1620, and periodically thereafter

Obesity and Metabolic Disease Impair the Anabolic Response to Protein Supplementation and Resistance Exercise: A Retrospective Analysis of a Randomized Clinical Trial with Implications for Aging, Sarcopenic Obesity, and Weight Management

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Patients on the 36 mg dose achieved an average weight loss of 11.2 percent over 72 weeks, compared to just 2.1 percent for placebo