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Manufacturers are seeking to improve efficacy by developing new dual- and tri-agonists, studying combinations, and offering more potent doses

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What does this mean for patients & our practice GLP-1 treatment with semaglutide can offer cardiovascular protection beyond pure weight loss, a potentially valuable tool in treating overweight, together with established cardiovascular disease

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On the basis of several putative modes of action under investigation (for example, neuroprotective and anti-inflammatory properties, regulation of reward pathways), there is an emerging consensus that GLP-1RAs could be repurposed for use in neuropsychiatric conditions 25,26,27,28,29,30,31,32