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Metabolic Plasticity of Tumor Cell Mitochondria

Dysfunction of T and B cells drives anti-nuclear antibody production through the release of oxidized immunogenic nuclear materials from necrotic rather than apoptotic cells (Perl 2013)

Zetterberg, H

Plasmids of wildtype and mutants of ARE motifs were transfected to K562 (#CRL-3344, ATCC), an erythroleukemia cell, along with pDsRed1-N1 (PT3405, Clontech), which is used as a transfection efficacy control

Cells with genetic predispositions, such as those with mutations in the MC1R gene or lower melanin levels, exhibit impaired DNA repair mechanisms, increasing their susceptibility to melanoma development 54

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