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Description
This CNS GLP-1 system does not seem to be activated by peripherally-secreted (endogenous) GLP-1 and therefore may be distinct from the peripheral GLP-1 system

Support Your GLP-1 Therapy Journey Reduce Side Effects & Maximize Results

The major side effect of nausea (also associated with bariatric surgery) at the start of treatment induces some patients to stop therapy, but most battle through this phase
In major markets such as the United States and Europe, semaglutide will remain protected into the early 2030s

22 To make a well-informed, individualized decision, it is essential to recognize the variability in both therapeutic benefits and adverse effects among patients treated with GLP-1 RAs

The STEP 1 extension study showed approximately two-thirds of weight was regained within one year of stopping semaglutide