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This narrative reviewaims to analyzecurrent findings on the beneficial and adverse ocular effects of GLP-1RAsuse, highlighting studies that elucidate the harmful causes, such as retinal microvascular dysregulation, inflammatory modulation, oxidative stress,osmotic dysregulation from sorbitol accumulation,and metabolic shifts

In recent years, GLP-1 role in neuronal pathways has expanded its therapeutic potential

Gastrointestinal (GI) adverse eventsparticularly nausea, vomiting, diarrhea, and constipationare the most common side effects, generally emerging during dose escalation and resolving over time