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In this article, we present a new method using currently available in silico tools to estimate the immunogenic potential of peptides containing UAA

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position 8, where alanine is substituted by alpha-aminoisobutyric acid and thus increasing resistance to DPP-4 degradation, position 34, where lysine is changed by arginine and thus, preventing wrong binding of C-18 fatty acid, and position 26, where lysine is a acylated with a glutamate spacer 15 to provide specific binding to albumin

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