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doi: 10.2337/db13-0227
We also examined two meta-analyses: one around the efficacy and safety of incretin therapy, and the other comparing exenatide once-weekly or liraglutide once-daily with insulin glargine, exenatide twice-daily or placebo
137: 127131 [DOI] [PubMed] [Google Scholar] 134.Yamada C, Yamada Y, Tsukiyama K, et al
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Now this all assumes that youve tried and failed other medications and treatments, though
Another plausible mechanistic explanation for a diminished incretin effect is the TCF7L2 -dependent repression of GLP-1R and GIPR expression on the -cells [569]
