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-1.1% using dulaglutide in the SUSTAIN-7 trial

The standard eligibility criteria require either a BMI of 30 or higher, or a BMI of 27 or higher combined with at least one weight-related health condition

Importantly, clinicians do not interpret this as drug failure

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Obesity with hepatic steatosis : Patients with BMI 30 kg/m (or 27 kg/m with weight-related comorbidities) and documented fatty liver may benefit from GLP-1 agonists approved for chronic weight management

Improper storage, repeated freeze-thaw cycles, excessive agitation, or poor reconstitution techniques may compromise experimental reproducibility