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Research-Backed Benefits of GLP-1s In clinical trials, GLP-1s lead to weight reductions of 518%, up to 25% after about 5672 weeks of use

In a recent double-blind randomized controlled trial, supplementation of A. muciniphilia for three months in obese participants demonstrated improved insulin sensitivity (+28.627.02%, P=0.002), and reduced insulinemia (34.087.12%, P=0.006) compared to placebo [9]. These effect sizes are not only statistically significant, they are also clinically significant and quite impressive for just administration of a single ingredient. This was a proof of concept study and we will update this page as more human literature is published investigating the metabolic effects of A. muciniphilia supplementation

Research from the STEP trials, which studied semaglutide 2.4mg weekly, found that approximately 75% of the weight lost was fat mass rather than lean mass

Always consult your physician before pursuing any treatment plan

If you do need to discontinue treatment, youre not completely without options

Nonetheless, brain regions with incomplete BBB, such as the subfornical region and the AP, are main targets of peripherally injected 125I-labeled GLP-1 [754]
