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Dual-agonist and tri-agonist therapies have demonstrated superior outcomes in weight loss, lowered blood sugar and lipid levels, restoration of tissue function, and enhancement of overall substrate metabolism compared to using GLP-1R agonists alone

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Healthcare professionals can assess hydration status, perform relevant investigations (such as stool cultures if indicated), and determine whether hospital admission for intravenous fluids or further management is necessary

Obesity, dyslipidemia, and cardiovascular disease: A joint expert review from the Obesity Medicine Association and the National Lipid Association 2024