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While synthetic GLP-1 receptor agonists (RAs) like semaglutide and tirzepatide dominate clinical use, plant-derived GLP-1 modulators present a promising alternative due to their natural origin, diverse mechanisms, and potential for reduced side effects

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Conclusion Customized treatment plans tailored to each patients needs, preferences, goals and circumstances should be considered for the treatment of antipsychotic and mood stabilizer-associated weight gain.

Semaglutide has transformed weight management for millions, but questions about safety and long-term use persist

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At higher doses, reductions exceeded 40%