semaglutide purpose Comparative safety and side effects of and tirzepatide: Implications for clinical decision-making in obesity management Benefits of Semaglutide GLP-1 Near
Description
The first twincretin was a unimolecular dual GLP-1R/GIP receptor (GIPR) agonist

Keep in mind that microdosing does not make the medication less effective

Nat Rev Endocrinol 19(11):655670

9,11 Among GLP-1 agonists, only liraglutide is currently FDA-approved for weight-loss in non-diabetic patients

Soucie, S
These medications are contraindicated in pregnancy and require discontinuation before conception (approximately two months for semaglutide)
