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In this Review, Cowie and Fisher describe the additional mechanisms of benefit of SGLT2 inhibitors, unrelated to improved glycaemic control.

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WEGOVY(semaglutide) injection 2.4 mg is an injectable prescription medicine that may help adults and children aged 12 years with obesity (BMI 30 for adults, BMI 95th percentile for age and sex for children), or some adults with excess weight (BMI 27) (overweight) who also have weight-related medical problems to help them lose weight and keep it off
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