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6.5 The Strategic Map Summarized across the four transactions, the triple-agonist deal map splits along two axes: modality (peptide injection versus oral small molecule versus oral peptide) and geography (in-house U.S./EU discovery versus Chinese licensing versus Korean licensing)

This extended duration of action improves patient compliance while maintaining consistent therapeutic effects throughout the treatment period

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Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions

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Clinical studies have shown that patients taking oral semaglutide achieved significant weight reduction over periods of up to 68 weeks