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It plays a role in appetite signaling, insulin secretion, and gastric emptying

Another potential problem

Some weight loss medications raise concerns about lean mass reduction

Here, we review therapies that combine GLP-1R pharmacotherapeutics with other weight loss mechanisms, which result in superior effects on body weight reduction and glucose metabolism

The most commonly reported side effects typically involve the gastrointestinal system, including nausea, diarrhea, vomiting, constipation, and abdominal pain

Almost 50% of the United States population has a chronic disease, and 86% of healthcare costs are attributed to treating them