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[209].Leone-Bay A, Grant M, Greene S, Stowell G, Daniels S, Smithson A, Villanueva S, Cope S, Carrera K, Reyes S, Richardson P, Evaluation of novel particles as an inhalation system for GLP-1, Diabetes, obesity & metabolism, 11 (2009) 10501059

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But the really impressive numbers came from the SURPASS-5 trial, where tirzepatide reduced total cholesterol by 12.9%, LDL cholesterol by 15.5%, and triglycerides by a substantial 24.9%, while increasing HDL cholesterol by 0.9%