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For example, the SELECT trial revealed that patients on semaglutide maintained an average weight loss of -10.2% over four years (208 weeks), while the placebo group only saw a modest -1.5% reduction

For instance, in September 2025, Pfizer announced plans to acquire Metsera, entering into a definitive agreement

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Data Availability Statement No new data were created or analyzed in this study.

Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial