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Adults struggling with insulin resistance or prediabetes: When your body isnt processing blood sugar effectively, it can lead to stubborn weight gain, fatigue, and cravings

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FIGURE 2 Inducing PDA Initiation Hyperinsulinemia induces chronic inflammation in the microenvironment of pancreatic ductal cells through recruiting fat deposition in pancreatic tissue and stimulating pancreatic fat tissue to secrete inflammatory factors under T2DM circumstances

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Despite metformins ability to lower glucose levels by boosting GLP-1 secretion in living organisms, it did not have the same effect on GLP-1 secretion in L cells during laboratory experiments (Mulherin et al., 2011)
