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In patients with IIH, abrupt cessation of GLP-1RA therapy has been reported to lead to a return of symptoms or new onset IIH in two separate case reports, highlighting the requirement of continuous therapy (22,24)

Potential implications of the new pharmacotherapies on obesity management The mean WL in clinical trials with the most efficacious new obesity pharmacotherapies ranges between 15% and 25% at 1 year (and it may be even higher for some agents that have not reached weight plateau at study completion)

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