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However, GLP-1 from dietary sources has a very short half life compared to GLP-1 half life from medications

It means that for most people, obesity is a chronic condition requiring ongoing treatment, similar to high blood pressure or diabetes

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Ethics Approval and Consent to Participate The study was approved by the Ethics Committee of Shijiazhuang Peoples Hospital (Approval No: 2025075)

Given the impairment in DPP4i action evident in HFD-fed mice, we wondered whether DPP-4 inhibition retained its hypolipidemic actions in older mice