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it's the volume that allows SNAC to work

Wong and colleagues applied body mass index and other risk factor changes to cardiovascular disease risk scores among an estimated 83 million persons without pre-existing cardiovascular disease, estimating a reduction in 10-year cardiovascular disease risk of 1.8% from 10.15% to 8.34% (or a relative risk reduction of 18%), projecting up to 1.5 million cardiovascular events could be potentially prevented in 10 years

However, SCFA-induced increases in PYY secretion should not be overlooked because PYY has a strong bone resorption-promoting effect

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Larger, long-term studies are needed to confirm their effectiveness, especially in patients without metabolic conditions, to clarify their role in psoriasis treatment