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As a result, scientists are increasingly attempting to combine GLP-1 RAs with other hormone-based medications or engineer them as dual or triple receptor agonists to enhance their efficacy in treating obesity while mitigating side effects

Behaviour change still matters

detected GLP-1R protein expression by immunohistochemistry in mouse coronary endothelial and smooth muscle cells [35]

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GLP-1R agonists may improve the function of the gut-brain axis and stability of the gut microbiota Many recent reports also emphasize the role of the gut-brain axis and stability of the gut microbiota in the development of mood disorders, including depression