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Those changes were associated with dysbiosis and a reduction in SCFAs in the colon of DIO mice

Brains were then snap-frozen in isopentane and the OB was cut into 18 m-thick sections afterwards, using a cryostat (Leica Biosystems)
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[DOI] [PMC free article] [PubMed] [Google Scholar] [24].Damstra-Oddy JL, Warren EC, Perry CJ, Desfougres Y, Fitzpatrick JMK, Schaf J, et al

Some conditions that Zofran is known to treat include generalized nausea, nausea and vomiting caused by chemotherapy, postoperative nausea, gastroparesis, pregnancy-associated nausea, gastroenteritis, and more
