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The Glucagon-like Peptide 1 (GLP) Receptor as a Therapeutic Target in Parkinsons Disease: Mechanisms of Action
GLP-1 medications work by mimicking the natural GLP-1 hormone in the body
The observed interactions between the ECD and ECL1/3 in the inactive GLP-1R structure presented here agree with previous studies suggesting that the ECD stabilized an inactive state of the glucagon receptor through interactions with ECL1 and ECL3 20

Am J Pathol 182:375387

Trials (2019) 20:191
