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Cureus 15 , e42153 (2023)

Oral bioavailability for peptides is generally lower than injectable delivery, which is why the daily dosing schedule exists

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After a meal, intestinal GLP-1 release triggers insulin secretion, slows gastric emptying, and signals satiety to the brain

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Diabetologia 2016;59:11121120 [DOI] [PMC free article] [PubMed] [Google Scholar] 42.Mann JF, Brown Frandsen K, Daniels G, et al
