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An analysis of 18 randomized control trials comparing the effects of GLP-1 RAs, SGLT-2 inhibitors, and Metformin demonstrated that semaglutide, dapagliflozin, ipragliflozin, and canagliflozin showed a significant weight loss in comparison with placebo treated controls (6)

First global approval

Research indicates that the activation of GLP-1R can alter the polarization of microglia, shifting them from a proinflammatory (M1) phenotype to an anti-inflammatory (M2) phenotype (Qian et al., 2022)

More than regulating your blood sugar, these medicines also work with your bodys natural hormones to help you feel full when eatingand for a longer period after meals

Do not skip doses or discontinue therapy without medical guidance, as weight regain commonly occurs after stopping GLP-1 medications

Cause 5: Electrolyte Imbalance Electrolytes including sodium, magnesium, and potassium play a critical role in regulating muscle contractions throughout the body