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This role operates exclusively in states that grant NPs full independent practice and prescriptive authority without a collaborative practice agreement or physician supervision

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Overview of Efficacy, Side Effects, and Key Challenges GLP-1 receptor agonists such as semaglutide and liraglutide, as well as combination agents like tirzepatide (which adds glucose-dependent insulinotropic polypeptide receptor agonism)all hereafter referred to as GLP-1s for brevityare effective new agents for obesity treatment which demonstrate weight reduction, weight maintenance, and reduced morbidity and mortality

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Leptin activates ROCK to alter actin dynamics in cardiomyocytes in JAK2/PI3K axis dependent way [141]

10.7554/eLife.54083 [DOI] [PMC free article] [PubMed] [Google Scholar] Sdzikowska A., Szablewski L