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37 Wulffel, M.G., et al., Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial

It's important to remember that Ozempic is not licensed for weight management in the UK

Future controlled trials are necessary to assess the associations of semaglutide with CUD

Extended-release formulations allow once-daily dosing

Xu F, Lin B, Zheng X, Chen Z, Cao H, Xu H, et al

But the null finding is notable because it suggests that GLP-1 appetite suppression may already be near the ceiling of what appetite reduction can achieve, leaving little room for phentermine to add benefit