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However, complex diseases such as obesity, type 2 diabetes, and neurodegenerative disorders are increasingly understood as network-level dysregulations rather than single-pathway failures

Interaction with diabetes medications in relation to ethnicity and dietary intake should be taken into account more rigorously in future studies

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This phenomenon, known as early worsening of diabetic retinopathy, has been documented with various diabetes treatments and is not unique to GLP-1 receptor agonists

[1] [2] Less common but important side effects include: Hypoglycaemia particularly when Rybelsus is used in combination with insulin or sulphonylureas