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Additionally, GLP-1 receptor agonists reduce gastrointestinal motility more broadly, which may contribute to sensations of bloating, fullness, and the need to expel gas orally

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Some people may experience mild side effects for longer than others

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Severe nausea requiring treatment discontinuation was rare in monotherapy trials, with only about 1% of participants in the REDEFINE 1 trial stopping treatment because of adverse events overall

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