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Diabetes Obes Metab 22(1):5158

If you also have an overactive thyroid as the underlying cause of your tremor, see your endocrinologist before starting Mounjaro, as significant weight loss can change how much thyroid hormone you need

While correlative data such as these cannot establish causality, the observation that women are also more likely than men to discontinue these medications strengthens the interpretation that the efficacy-to-tolerability ratio for these drugs is lower for women (Fig

A network meta-analysis found retatrutide produced greater mean weight reduction, though it also showed higher overall adverse event rates

Exp Ther Med 22(5):1265

However, the medications mechanisms of action can indirectly influence hormonal balance
