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If you're planning to conceive, discuss discontinuing GLP-1 therapy with your healthcare provider beforehand

Let's be honest, though

doi:10.2214/ajr.154.1.2104734

Clinical trials used 12mg as the maintenance dose throughout the study period

Adv Mater

ATTAIN-1 (NCT05869903) The key trial for the obesity indication, ATTAIN-1 randomized 3,127 adults with obesity or overweight (without diabetes) to orforglipron 6 mg, 12 mg, or 36 mg versus placebo for 72 weeks
