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Easier to recover from on GLP-1 drugs: Moderate-intensity resistance training with controlled tempo (3-second eccentric) Lower total volume sessions (8 to 12 working sets) Walking and low-intensity steady-state cardio Mobility and flexibility work Harder to recover from on GLP-1 drugs: High-volume bodybuilding-style sessions (20+ sets) High-intensity interval training (HIIT) Heavy eccentric-focused training (slow negatives, drop sets) Two-a-day training sessions Endurance workouts over 60 minutes at moderate-to-high intensity The common thread: anything that creates significant muscle damage or glycogen depletion will take longer to recover from when calories are restricted

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In the pancreas, they stimulate glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications

Its being studied for more (addiction, mental health, Alzheimers) Prices are coming down (Zepbound is 20% less expensive than Wegovy) But, on the other hand: Medicare is legally prevented from covering GLP1s for obesity Only 16 states cover anti-obesity medications under Medicaid 50% or less commercial plans cover GLP1s for obesity, and those that do often have unreasonable hurdles Covered can still mean $500-1000 out of pocket every month

Twenty-six weeks after stopping treatment, both groups had gained weight, but compared to the initial period, the liraglutide use group had gained 1.5% and the control group had gained 4.6%, suggesting that liraglutide was effective for weight management, even in adolescents

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