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Take it whenever suits, with a meal, with coffee, with a full glass of water, alongside other medicines

avoid eating close to bedtime Ginger and bland foods : Some patients find ginger tea or bland foods (toast, crackers, rice) helpful during episodes of nausea Slow eating : Chew food thoroughly and eat slowly to reduce gastric distress If nausea is severe or persistent, contact your GP or diabetes specialist nurse

Several tools can help

Nature (2002) 418(6898):6504

Any new or worsening symptoms after months of stable therapy should be evaluated, as these may indicate complications unrelated to expected medication effects

It sounds like someone who's really done their research