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NanoBiT complementation assays GLP-1R-SmBiT WT was previously cloned in house as described in (28)

The profile of a typical heart disease patient has shifted over the past 30 years from the hypertensive, chain-smoking, type A personality to someone with overweight or obesity and concomitant diabetes

At steady state, ecnoglutide C trough concentrations showed approximate dose proportionality over the range of 0.41.2 mg

Liver fat reduction by dose At the 1mg dose, liver fat decreased by 42.9% at 24 weeks
