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GLP-1 agonists offer metabolic and anti-inflammatory benefits, but appetite suppression may drive gut microbiome dysbiosis that offsets long-term outcomes.

It also raises the risk of sarcopenia the age-related loss of muscle mass and function that contributes to frailty, falls, and reduced quality of life

Practical guidance on safe prescribing, protein, bone support, and exercise tailored for older adults considering GLP-1 therapy.

Despite great progress in GLP-1R structure determination, our understanding on the differences of peptide binding and signal transduction between these two receptors remains elusive

Learn more about these revolutionary GLP-1 medications.

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