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Semaglutide is recommended as an option: As monotherapy when metformin is contraindicated or not tolerated, or In dual or triple therapy combinations when a GLP-1 receptor agonist is appropriate (for example, when further glucose control is needed and weight loss would be beneficial, or when other treatments are unsuitable)

Regarding approved uses, tesofensine is specifically used to treat obesity, while semaglutide is indicated for both type 2 diabetes and obesity management

However, the pills are only available through private prescriptions for now, and will only be prescribed on the NHS if they get approval from the National Institute for Health Care Excellence

This combination not only suppresses appetite but also promotes calorie burning, which makes it a multi-pathway approach to weight management

Week 14 begins at 0.25 mg weekly, then increases to 0.5 mg for weeks 58, followed by 1.0 mg for weeks 912, and continuing upward by 0.25 mg increments every 4 weeks until your provider determines your therapeutic target

What Are the Side Effects of Semaglutide